期刊名称:Journal of Education and Teaching in Emergency Medicine
印刷版ISSN:2474-1949
出版年度:2019
卷号:4
期号:1
页码:1-3
DOI:10.21980/J8B06Z
出版社:University of California Press
摘要:History of present illness: A 59-year-old male with a history of end stage renal disease on hemodialysis was
sent to the emergency department (ED) by his dialysis center for concern for left upper extremity graft
infection. The patient denied pain, fever, chills, or redness at the site. He did note a mass with a pustule at
the fistula site that started that day, but there was no active drainage.
In the ED, the patient was well appearing, afebrile, with a normal heart rate and in no distress. Examination
of the left upper extremity revealed a 1 cm mass with a sub centimeter discoloration of the overlying skin at
the active fistula site. There was a palpable thrill and audible bruit.
Significant findings: A bedside ultrasound of the mass demonstrated a large compressible hypoechoic
structure (see purple outline) above the arteriovenous graft (see red outline). The contents demonstrated
movement of fluid within the structure. This was confirmed with Doppler mode, which allowed for
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visualization of flow communicating between the structure and the underlying vessel, which is diagnostic for
a pseudoaneurysm.
Discussion: Vascular access (VA) complications involving either arteriovenous graft (AVG) or arteriovenous
fistula (AVF) represent 36%-39% of hospitalizations in hemodialysis patients.1,2 Major complications include
stenosis, thrombosis, infection, congestive heart failure, ischemic neuropathy, steal syndrome, and
aneurysm. VA associated aneurysms can be divided into two groups: true and pseudoaneurysms. True
aneurysms, which involve all layers of the vessel wall, are seen most often with AVFs and are mostly
asymptomatic. In contrast, pseudoaneurysms occur outside the vessel wall due to a communicating defect
in the graft. They are essentially hematoma encapsulated in adventitia that are prone to rupture.
Pseudoaneurysms are a relatively rare complication of vascular access with an incidence of 2%-10%.3 They
often result from weakening of the vessel wall secondary to inflammation from infection or chronic needling
which leads to scarring.4 Concerning signs that warrant vascular surgery consultation include an aneurysm
that is symptomatic, twice the size of the graft, expanding, threatened viability of overlying skin, or
large/multiple aneurysms limiting number of cannulation sites.5 Doppler ultrasound is the principal means of
diagnosis with a sensitivity of 94%.6 On ultrasound there are several characteristic findings that can alert the
provider to the diagnosis of pseudoaneurysm. On color doppler, visualization of a communication between
the vessel and fluid collection external to the vessel is diagnostic.7 This connection is classically described as
the yin-yang sign.7 Spectral doppler can demonstrate biphasic flow through the communication.7
The patient discussed here was seen by vascular surgery and admitted for surgical evaluation. After further
records were obtained, the patient was found to have a history of three prior surgically removed
pseudoaneurysms. Ultimately, he had ligation and excision of the graft two days later revealing two pulsatile
pseudoaneurysms along the mid graft. The graft was unable to be salvaged, and he was scheduled for
creation of a new fistula in the right arm.
Key points that guide the management of this case are the identification of changes overlying the fistula in
the acute setting, prompting the use of bedside ultrasound, and necessitating vascular consultation. Any
mass concerning for infection near a fistula or graft site should make a physician wary of possible aneurysm.