摘要:"Background: In the absence of any intervention transmission of Human Immunodeficiency Virus (HIV) from a HIV positive mother to her child during pregnancy, labour, delivery or breastfeedingranges from 15%-45%. This rate can be reduced to below 5% with effective interventions1.Present study was carried out to know the seroprevalence of HIV infection over twelve years amongst antenatal women attending a tertiary care hospital in western India along with analysis of their demographic data. Methods: After due permission from Institutional Review Board,studywas carried out by analyzing the data of antenatal women in whom HIV testing was done as per National AIDS Control Organization (NACO) guidelines from 1/4/2004 to 31/03/2016. Results: Overallseroprevalence of HIV infection amongst antenatal women was 0.31% and of 2014-2016 was 0.17%. Maximum number of women, 93(44.28%) were in age group of 25-29 years. Primigravida were 89(42.38%). Majority 165(78.57%) were from urban area. Conclusion: Ours was a hospital-based study with limited sample size. The steady decline in seroprevalence of HIV could be attributed to effective awareness-education programs by NACO as well as efforts by the medical-paramedical staff and counselors at our institute.