摘要:Background and Objectives: Nigella sativa is the scientific name for black cumin or habbatussauda. Nigella sativa seeds contain oil commonly used for medicinal purposes to treat various diseases. Nigella sativa meal (NSM) is a by-product from the industry that extracts the oil. NSM contains a high protein content and can be used as a source of protein in the diet. The purpose of this research was to evaluate the effect of using NSM as a feed on the growth performance, metabolite and blood profile and nutrient digestibility of lambs. Materials and Methods: This study used a randomized block design with 5 replicates of 3 treatments using 15 local Indonesian male lambs. The concentrations of NSM in the rations were 0, 10 and 20%, with a maintenance period of 56 days. The forage to concentrate ratio was 30:70. Results: The average daily weight gain and blood urea nitrogen (BUN) concentration of the experimental animals were significantly (p<0.05) higher for the diets that contained 10 and 20% NSM (T1 and T2) compared to those for all other treatment groups. Additionally, the use of NSM in the diet improved the digestibility of crude protein , nitrogen retention and nitrogen use efficiency, with the mean biological value of protein being higher for the diet that contained NSM T1 (99.51) and T2 (99.44) compared to that for the control treatment group T0 (98.09). Conclusion: When the concentration of NSM reaches 20% in lamb rations, it has the most effect on growth performance and nutrient efficiency without affecting the metabolite and blood profiles, which remain in the normal range.