The purpose of this study is to examine the relationship between high school students’ social support, career adaptability and subjective well-being that are perceived from their family, teachers and friends. The study group consisted of 325 students (193 girls, 132 males) in three secondary schools located in Cukurova and Yuregir districts of Adana city. The data were collected through Career Adaptability Scale, Life Satisfaction Scale, Positive and Negative Affect Schedule and Perceived Social Support Scale and Personal Information Form developed by the researchers to reach the demographic information of the participants. A path analysis was conducted within the framework of structural equation modeling to investigate the relationship between social support, career adaptability and subjective well-being that the students perceived. Data analysis was done through SPSS and AMOS package programs. Correlation coefficients of arithmetic mean, standard deviation, pearson moment analysis were calculated, and path analysis was performed based on the observed variables. The research findings show that there is a significant relationship between subjective well-being, career adaptability and perceived social support. The perceived social support from family, teachers and friends are variables that predict the career adaptability of high school students. Career adaptability has also been found to be a significant predictor of subjective well-being.