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  • 标题:Drug Target Commons 2.0: a community platform for systematic analysis of drug–target interaction profiles
  • 作者:Tanoli, ZiaurRehman ; Alam, Zaid ; Vähä-Koskela, Markus
  • 期刊名称:Database
  • 印刷版ISSN:1758-0463
  • 电子版ISSN:1758-0463
  • 出版年度:2018
  • 卷号:2018
  • 期号:1
  • DOI:10.1093/database/bay083
  • 出版社:Oxford University Press
  • 摘要:Drug Target Commons (DTC) is a web platform (database with user interface) for community-driven bioactivity data integration and standardization for comprehensive mapping, reuse and analysis of compound–target interaction profiles. End users can search, upload, edit, annotate and export expert-curated bioactivity data for further analysis, using an application programmable interface, database dump or tab-delimited text download options. To guide chemical biology and drug-repurposing applications, DTC version 2.0 includes updated clinical development information for the compounds and target gene–disease associations, as well as cancer-type indications for mutant protein targets, which are critical for precision oncology developments.
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