文章基本信息

标题：Hormonal replacement therapy and morbidity and mortality in a prospective study of postmenopausal women.
本地全文：下载
作者：A R Folsom ; P J Mink ; T A Sellers 等
期刊名称：American journal of public health
印刷版ISSN：0090-0036
出版年度：1995
卷号：85
期号：8 Pt 1
页码：1128-1132
出版社：American Public Health Association
摘要：We assessed the association of hormonal replacement therapy with mortality and incidence of multiple diseases in over 40,000 postmenopausal women followed for 6 years as part of the Iowa Women's Health Study. Compared with women who never used hormone replacement therapy, current users had multivariate adjusted relative risks (RR) as follows: total mortality (RR = 0.78; 95% confidence interval [CI] = 0.65, 0.94), coronary heart disease mortality (RR = 0.74; 95% CI = 0.48, 1.12), endometrial cancer incidence (RR = 4.3; 95% CI = 2.7, 6.9), breast cancer incidence (RR = 1.23; 95% CI = 0.99, 1.55), colon cancer incidence (RR = 0.72; 95% CI = 0.46, 1.12), and hip fracture incidence (RR = 0.53; 95% CI = 0.31, 0.91).