摘要:Background: Risk taking behaviour refers to the tendency to engage in behaviours that have the potential to be harmful or dangerous, which has become a major concern and is rated as one of the public health issues that need special attention. The objective of the study was to compare the prevalence of risk taking behaviour and its associated factors among urban and rural adolescents. Methods: A comparative cross-sectional study was conducted among 306 adolescents by multistage sampling from two selected schools with involvement of their parents. Results: The prevalence of risk taking behaviours was 81.7% in the urban and 83.7% in the rural area (p = 0.650). Parental background factors such as parent’s education level, marital status, health status, and income were unrelated with risk taking behaviour among adolescents. The multiple logistic regression test showed that being a male (AOR = 4.55, 95% CI = 2.28–9.07), inadequate number of bedrooms (AOR = 11.54, 95% CI = 1.48–89.75), and presence of family conflict (AOR = 3.64, 95% CI = 1.49–8.89) were the predictors among adolescents for risk taking behaviour in rural areas. Conclusion: The absence of a balanced healthy family and conducive environment would lead to a negative influence towards adolescent behaviour, which may affect both the individual and community.