摘要:Objectives. This study determined trends in diabetes prevalence among young American Indians and Alaska Natives. Methods. American Indian and Alaska Native children (< 15 years), adolescents (15–19 years), and young adults (20–34 years) with diabetes were identified from the Indian Health Service (IHS) outpatient database. The population living within IHS contract health service delivery areas was determined from census data. Results. From 1990 to 1998, the total number of young American Indians and Alaska Natives with diagnosed diabetes increased by 71% (4534 to 7736); prevalence increased by 46% (6.4 per 1000 to 9.3 per 1000 population). Increases in prevalence were greater among adolescents and among young men. Conclusions. Diabetes should be considered a major public health problem among young American Indians and Alaska Natives. Type 2 diabetes has been recognized as a significant public health problem in American Indian communities for almost 40 years. 1, 2 The Pima Indians in Arizona have the highest recorded prevalence of diabetes in the world. 3 Compared with other US populations, American Indians and Alaska Natives have been disproportionately affected with diabetes since the early 1960s, 1 and its increasing prevalence in this population has been documented since 1983. 2, 4 Although type 2 diabetes has traditionally been regarded as a disease of adults, 5 its prevalence among children and youth has emerged as a public health concern for American Indian communities. 6 As early as 1979, young Pima Indians were noted to have a high prevalence of type 2 diabetes. 7 More recently, the emergence of type 2 diabetes among children and adolescents has been described in other US populations, such as African Americans and Hispanics, and among Canada’s First Nations. 8 The American Diabetes Association issued a statement in 2000 alerting the health care community to the growing problem of type 2 diabetes among children and adolescents. 9 Among American Indian and Alaska Native adults, diabetes is a major cause of morbidity (such as blindness, kidney failure, lower-extremity amputation, and cardiovascular disease), disability, decreased quality of life, and premature mortality 2 as well as a major cause of congenital anomalies, malformations, and perinatal death. 10 Little is known, however, about the prevalence of diabetes among young American Indians and Alaska Natives in the United States and how this prevalence varies geographically. The purpose of this study was to determine the magnitude of this public health problem and to document national and regional trends in diabetes prevalence among young American Indians and Alaska Natives. Additionally, we describe initial efforts in affected communities to address prevention of diabetes among young people.