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  • 标题:Kaposi Sarcoma in HIV Infected Patients
  • 作者:Raluca Jipa ; Oana Săndulescu ; Eliza Manea
  • 期刊名称:Acta Medica Marisiensis
  • 电子版ISSN:2247-6113
  • 出版年度:2016
  • 卷号:62
  • 期号:2
  • 页码:285-288
  • DOI:10.1515/amma-2016-0019
  • 语种:English
  • 出版社:Walter de Gruyter GmbH
  • 摘要:Objective : The aim of the study was to describe clinical and laboratory characteristics in HIV-infected patients with Kaposi sarcoma (KS). Methods : We retrospectively studied data on HIV-infected patients hospitalized in one tertiary care hospital in Bucharest, Romania, in whom Kaposi Sarcoma was diagnosed, between January 2008 and November 2013. Results : We identified 27 HIV-infected patients diagnosed with KS within 6 years. They had a median age of 42 years old and a median CD4 cell count of 101 cells per mm3 at the time of KS diagnosis. All patients received antiretroviral therapy (ART), with 18 patients (66%) already on ART at the time of KS diagnosis. Most patients (59%) were classified as ACTG poor-risk and 56% as Mitsuyasu stage I. The overall prognosis was poor, with 41% mortality, in a median time span of 6 months, significantly correlated with gastrointestinal involvement (p=0.019), poor-risk KS in ACTG classification (p<0.001) and stage IV Mitsuyasu (p=0.006). Conclusion : KS remains an important cause of morbidity and mortality in patients with HIV infection, especially in late presenters.
  • 关键词:Kaposi disease ; HIV ; late presenters
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