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标题：Physical activity as a protective factor against development of liver steatosis in patients infected with hepatitis C
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作者：Lucas de Lucena Simões e Silva ; Matheus Santos de Souza Fernandes ; Eline Autran de Lima 等
期刊名称：Biomedical Human Kinetics
电子版ISSN：2080-2234
出版年度：2018
卷号：10
期号：1
页码：89-94
DOI：10.1515/bhk-2018-0014
语种：English
出版社：Walter de Gruyter GmbH
摘要：Study aim: Was to verify whether the regular practice of physical activity promotes some protective factor against the development of LS in patients infected with hepatitis C virus (HCV). Materials and method: Clinical data were obtained through medical records available at the Pernambuco Liver Institute. Physical activity levels were obtained through the International Physical Activity Questionnaire (IPAQ) short form to classify the patients according to the guidelines of the American College of Sports Medicine (ACSM). Results: The sample consisted of patients of both genders, over 18 years of age, who had positive anti-HCV, HCV-RNA and confirmatory tests for presence or absence of liver steatosis. 126 patients were included in the study. Patients with liver steatosis (G1) were more frequently male (57%) compared to patients without liver steatosis (G2) (p = 0.02). Physical activity analysis showed significant differences for GGT (p = 0.04), HDL (p = 0.04), AF (p = 0.02), viral genotype 3 (p = 0.04) and waist-to-hip ratio (p = 0.01) in anthropometric data. Correlation analysis showed a significant difference for GGT (r = -0.23; p = 0.01) and total bilirubin (BT) (r = -0.22; p = 0.01). Conclusions: Regular practice of physical activity generates a protective factor against the development of LS in patients infected by the hepatitis C virus and it is associated with the maintenance of variables related to hepatic and biochemical damage in patients infected with HCV.
关键词：Physical activity - Hepatitis C - Fatty liver - Hepatology - Health