摘要：Earlier studies with antirabies serum and vaccine have been extended to determine the value of serum, vaccine, or serum and vaccine combined against rabies challenges of increasing degrees of severity. While serum alone was not found to have any protective effect, vaccine alone was sufficient against mild challenges, the superiority of combined therapy with both serum and vaccine becoming evident at a challenge of about 50 LD50. With challenges of over 300 LD50 no treatment was of any value. It was also found that with a recommended optimum dose of serum, the usual vaccine dose could be halved—a matter of importance in countries with a high incidence of neuroparalytic accidents following administration of nervous tissue vaccine. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.2M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 381 382 383 384 385 386 387 388 389 390 391
Loading...
