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标题：A large-scale field trial of malathion as an insecticide for antimalarial work in southern Uganda
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作者：J. A. Najera ; G. R. Shidrawi ; F. D. Gibson 等
期刊名称：Bulletin of the World Health Organization
印刷版ISSN：0042-9686
出版年度：1967
卷号：36
期号：6
页码：913-935
语种：English
出版社：World Health Organisation
摘要：Malathion shows promise as a substitute for chlorinated-hydrocarbon insecticides in the control of malaria whenever the latter are unsuitable because of Anopheles resistance or other reasons. A field trial of malathion was carried out in 1963-64, covering an area of about 500 km² with a population of about 26 000, in Masaka District, southern Uganda. All houses and animal shelters were sprayed with malathion at 2 g/m² at roughly 4-month intervals. The average combined densities of the females of the two main malaria vectors, Anopheles funestus and An. gambiae, fell from an average of 66 per shelter per day in a pre-trial survey in 1960-61 to 0.0011 at the end of 1964 in the sprayed area; no significant changes were noted in unsprayed comparison areas. The transmission of the infection in humans was apparently interrupted when allowance was made for imported cases. The presence of unsprayed surfaces in houses which had recently been built or altered interfered somewhat with complete coverage. Case detection was reliable and achieved excellent coverage. No toxic effects of malathion in humans were noted, while the effect on mosquitos was considerable even in the absence of direct contact. This effect of malathion lasted for a considerably shorter period of time in houses roofed with corrugated iron than with thatch; this should be borne in mind in the design of spraying programmes. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (3.2M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 913 914 915 916 917 918 919 920 921 922 923 924 925 926 927 928 929 930 931 932 933 934 935