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标题：Studies on the relationship between fluorescent antibody response and the ecology of malaria in Malaysia
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作者：William E. Collins ; McWilson Warren ; Jimmie C. Skinner 等
期刊名称：Bulletin of the World Health Organization
印刷版ISSN：0042-9686
出版年度：1968
卷号：39
期号：3
页码：451-463
语种：English
出版社：World Health Organisation
摘要：The fluorescent antibody (FA) technique was used to detect the presence of malarial antibody in populations living in 3 different ecological areas of Malaysia. Serum samples were tested using Plasmodium falciparum, P. vivax, P. malariae and P. fieldi antigens. An area of hyperendemic malaria had a good correlation between the antibody responses and active parasitaemias. The percentage and intensity of responses increased with the age of the individuals. In an area of hypoendemic malaria, each of 17 sites had ecological conditions which would favour or discourage the transmission of malaria. The reasons for high FA responses in some villages and low responses in others were readily apparent. The effect of even limited control programmes on the malarial ecology could be measured by an examination of the antibody responses. An aboriginal population receiving suppressive drugs had FA responses indicating both past experience and the effect of the drug programme. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.5M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 451 452 453 454 455 456 457 458 459 460 461 462 463