摘要：The study concerns 337 outpatients with lepromatous leprosy who had been receiving dapsone treatment for 1-26 years—69% of them regularly and 31% irregularly. Routine bacterial examination (10 min per slide) by a paramedical technician showed only 50% of these patients to be bacteriologically positive. This rate attained 99% when each slide was examined for 30-60 min by a qualified bacteriologist. Other factors—apart from the limited action of sulfones—might account for these unexpected results: the material was collected by an experienced leprologist; the disease was still clinically active in 75% of the patients; about 25% of them had been treated for only 1-4 years; and the intake of dapsone in long-term treatment gradually decreases. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (712K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 57 58 59 60 61 62
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