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标题：Detection of markers of hepatitis B infection in serum dried on to filter-paper: an application to field studies
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作者：Hui Zhuang ; Anthony G. Coulepis ; Stephen A. Locarnini 等
期刊名称：Bulletin of the World Health Organization
印刷版ISSN：0042-9686
出版年度：1982
卷号：60
期号：5
页码：783-787
语种：English
出版社：World Health Organisation
摘要：In an attempt to find a cheap, reliable, and convenient method for the transportation and storage of serum specimens during seroepidemiological surveys, a technique in which serum was dried on to pieces of filter paper was developed and evaluated. For the evaluation, a total of 382 sera were selected from the extensive serum collection held by the WHO Collaborating Centre for Virus Reference and Research at Fairfield Hospital, Australia. These sera were dried on to pieces of filter-paper, stored at different temperatures and then tested for the presence of the various markers of infection with hepatitis B virus by solid-phase radioimmunoassay. The results were in complete agreement with those obtained on whole serum specimens. In addition, storage at 4 °C, room temperature (22 °C), or 37 °C for up to 30 days did not alter the sensitivity of the test. This technique may be useful in field surveys, not only for the detection of hepatitis B infection, but also in the study of other diseases and metabolic disorders. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (588K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 783 784 785 786 787