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  • 标题:The effect of oral contraceptives in malaria infections in rhesus monkeys
  • 作者:William E. Collins ; Carlos C. Campbell ; Ann Barber
  • 期刊名称:Bulletin of the World Health Organization
  • 印刷版ISSN:0042-9686
  • 出版年度:1984
  • 卷号:62
  • 期号:4
  • 页码:627-637
  • 语种:English
  • 出版社:World Health Organisation
  • 摘要:Rhesus monkeys, Macaca mulatta, were treated with the oral contraceptives Brevicon (norethisterone with ethinylestradiol) and Ovral (norgestrel with ethinylestradiol), and subsequently inoculated with the simian malaria parasites Plasmodium cynomologi bastianellii or P. coatneyi. Parasitological, serological, and serum biochemical studies indicated that although there were some significant differences, in general the patterns of response to infection in both treated and control animals were similar. During the primary infection, however, Brevicon resulted in increased levels of parasitaemia, whereas Ovral resulted in decreased parasitaemias, as compared with the untreated control animals. There were no differences in the responses following secondary parasite infection. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1013K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 627 628 629 630 631 632 633 634 635 636 637
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