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  • 标题:Diagnosis of measles by clinical case definition in dengue-endemic areas: implications for measles surveillance and control.
  • 本地全文:下载
  • 作者:V. J. Dietz ; P. Nieburg ; D. J. Gubler
  • 期刊名称:Bulletin of the World Health Organization
  • 印刷版ISSN:0042-9686
  • 出版年度:1992
  • 卷号:70
  • 期号:6
  • 页码:745-750
  • 语种:English
  • 出版社:World Health Organisation
  • 摘要:In many countries, measles surveillance relies heavily on the use of a standard clinical case definition; however, the clinical signs and symptoms of measles are similar to those of dengue. For example, during 1985, in Puerto Rico, 22 (23%) of 94 cases of illnesses with rashes that met the measles clinical case definition were serologically confirmed as measles, but 32 (34%) others were serologically confirmed as dengue. Retrospective analysis at the San Juan Laboratories of the Centers for Disease Control showed also that at least 28% of all laboratory-confirmed cases of dengue in Puerto Rico in 1985 met the measles clinical case definition. If the true measles vaccine efficacy (VE) is assumed to be 90%, the occurrence of laboratory-confirmed dengue cases that meet the measles clinical case definition results in a reduction of the apparent measles VE to only 64% (a 29% relative reduction from the true VE). The results of the study demonstrate the importance of a laboratory-based surveillance system in measles control or elimination efforts in dengue-endemic areas. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (873K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 745 746 747 748 749 750
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