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  • 标题:Low seroconversion rates to measles vaccine among children in Nigeria.
  • 本地全文:下载
  • 作者:F. D. Adu ; O. A. Akinwolere ; O. Tomori
  • 期刊名称:Bulletin of the World Health Organization
  • 印刷版ISSN:0042-9686
  • 出版年度:1992
  • 卷号:70
  • 期号:4
  • 页码:457-460
  • 语种:English
  • 出版社:World Health Organisation
  • 摘要:The Nigerian Expanded Programme on Immunization (EPI) was assessed with particular reference to measles immunization. Of 150 children who received measles vaccine at the Institute of Child Health, University of Ibadan, Nigeria, 82 (54.7%) seroconverted. The immune response was directly related to the titre of the vaccines used. Vaccines whose titres were 10(-1) to 10(1.7) stimulated immune responses in 0-25% of vaccinees, those with titres in the range 10(-2.1) to 10(-2.5) stimulated responses in 12-47.6%, while those with titres of 10(-2.7) to 10(-3.4) stimulated responses in 87.5-100% of vaccinees. Only one of the vaccines used had a titre that met the minimum WHO required standard of log 10(-3) TCID50 at the point of vaccination. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (469K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 457 458 459 460
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