文章基本信息

标题：Use of bivariate lifetime distributions assuming continuous or discrete data applied to patients with breast cancer
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作者：Tatiana Reis Icuma ; Isabela Panzeri Carlotti Buzatto ; Daniel Guimarães Tiezzi 等
期刊名称：Journal of Data Science
印刷版ISSN：1680-743X
电子版ISSN：1683-8602
出版年度：2016
卷号：14
期号：4
页码：657-680
出版社：Tingmao Publish Company
摘要：Breast cancer is the second most common type of cancer in the world (World Cancer Report, 2014 a, b). The evolution of breast cancer treatment usually allows a longer life of patients as well in many cases a relapse of the disease. Usually medical researchers are interested to analyze data denoting the time until the occurrence of an event of interest such as the time of death by cancer in presence of right censored data and some covariates. In some situations, we could have two lifetimes associated to the same patient, as for example, the time free of the disease until recurrence and the total lifetime of the patient. In this case, it is important to assume a bivariate lifetime distribution which describes the possible dependence between the two observations. We consider as an application, different parametric bivariate lifetime distributions to analyze a breast cancer data set considering continuous or discrete data. Inferences of interest are obtained under a statistical Bayesian approach. We get the posterior summaries of interest using existing MCMC (Markov Chain Monte Carlo) methods. The main goal of the study, is to compare the bivariate continuous and discrete distributions that better describes the breast cancer lifetimes.
关键词：Bayesian analysis; Bivariate lifetime distributions; Breast cancer data; Continuous and discrete lifetime data; Right censored data and covariates.