文章基本信息

标题：Culter alburnus ) after oral administration
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作者：Wang W. ; Dai X. ; Li Z. 等
期刊名称：Czech Journal of Food Sciences
印刷版ISSN：1212-1800
电子版ISSN：1805-9317
出版年度：2009
卷号：27
期号：3
页码：214-221
DOI：10.17221/183/2008-CJFS
出版社：Czech Academy of Agricultural Sciences
摘要：The serum concentration and muscle residue of florfenicol following oral administration were evaluated in topmouth culter ( Culter alburnus ) under field conditions. Fishes were cultured in tanks and fed a commercial medicated diet containing 2000 mg/kg florfenicol in a single dose. The sampling was conducted at different intervals (0, 0.5, 1, 1.5, 2, 3, 4, 8, 10, 12, 16, 24, 36, 48, 72, 96, 120, 144, 168 h) after the cessation of medication. Drug analysis was carried out by HPLC. The maximum concentration ( C _max) of 10.8 μg/g in serum and 4.2 μg/g in muscle were reached at the same time ( t _max) of 8 hours. If the EU MRL value of 1.0 μg/g is quoted for the topmouth culter tissue, the extrapolation of the data indicated that it will be passed after a 40.6 h withdrawal period for florfenicol in topmouth culter muscle.
关键词：serum; elimination; florfenicol; topmouth culter ( Culter alburnus )