文章基本信息

标题：Discriminant Analysis of Rheumatoid Factor, Anti-Cyclic Citrullinated Peptide, and C-Reactive Protein for Rheumatoid Arthritis Patients
本地全文：下载
作者：Ausaf Ahmad ; T.B. Singh ; Usha 等
期刊名称：National Journal of Community Medicine
印刷版ISSN：0976-3325
电子版ISSN：2229-6816
出版年度：2017
卷号：8
期号：3
页码：148-152
出版社：National Journal of Community Medicine
摘要："Background: Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by joint swelling, joint tenderness, and de-struction of synovial joints, leading to severe disability and premature mortality with uncertain aetiology by signi?cant morbidity and mortality. Prevalence of approximately 0.75% in India. About 40% diseased become work disabled within 5 years from onset of symptoms. Objectives: The study was conducted to determine the most parsimonious way to distinguish between groups and to test the theo-ry by which cases are classi?ed as predicted. Method: The study is based on 290 clinically suspected RA patients. Cross-sectional study design was used. Clinically suspected cases were referred by different OPD’s of Sir Sunderlal Hospital for screening. Result: RF, AntiCCP and CRP diagnosed RA 21.3%, 21.7% and 33.1% respectively as positive . 277/290 (92.1%) of respondents were classi?ed correctly into ‘RA’ or ‘non-RA’ groups. Non-RA were classi?ed with better accuracy (98.8%) than RA (58.3%). Interpretation & Conclusion: Early diagnosis of these high risk suspects will help in preventing from foremost disability. The quality of life may be approved of infected subjects by providing timely diagnosis and treatments and balanced nutritional and social supports. "
关键词：Rheumatoid arthritis; discriminant analysis; Cross-sectional; classification