文章基本信息

标题：Anti-pseudomonal Effect of a Nephrite-containing Contact Lens Storage Case
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作者：Lee, Sang Min ; Jung, Jae Woo ; Lee, Dong Hyun 等
期刊名称：Journal of the Korean Ophthalmological Society
印刷版ISSN：0378-6471
出版年度：2018
卷号：59
期号：8
页码：724-729
DOI：10.3341/jkos.2018.59.8.724
语种：Korean
出版社：The Korean Ophthalmological Society
摘要：Purpose
To compare the anti-pseudomonal effect of nephrite-containing contact lens (CL) storage cases with conventional CL storage cases.
Methods
The degree of proliferation and adhesion of Pseudomonas aeruginosa ( P. aeruginosa ) on 1st–3rd generation silicone hydrogel contact lenses (SHCLs) was compared by using both 5% nephrite-containing CL storage cases and conventional CL storage cases. The degree of adhesion of P. aeruginosa to the CL was also compared in 1% or 5% nephrite solution and multipurpose solution (MPS).
Results
Nephrite-containing CL storage cases showed a significant inhibitory effect on P. aeruginosa proliferation ( p = 0.03) and significantly reduced the number of adherent P. aeruginosa on all 1st–3rd generation SHCLs compared with conventional CL storage cases ( p = 0.02, p = 0.03, and p < 0.01, respectively). There was no significant anti-pseudomonal effect of 1% and 5% nephrite solutions compared with MPS.
Conclusions
Nephrite may be the next generation substance that reduces infectious keratitis caused by P. aeruginosa when added to CL storage cases.
关键词：Contact lens storage case; Infectious keratitis; Multipurpose solution; Nephrite; Pseudomonas aeruginosa