首页    期刊浏览 2024年12月02日 星期一
登录注册

文章基本信息

  • 标题:Adherence to Nutrition and Physical Activity Cancer Prevention Guidelines and Development of Colorectal Adenoma
  • 本地全文:下载
  • 作者:Lindsay N. Kohler ; Robin B. Harris ; Eyal Oren
  • 期刊名称:Nutrients
  • 电子版ISSN:2072-6643
  • 出版年度:2018
  • 卷号:10
  • 期号:8
  • 页码:1098
  • DOI:10.3390/nu10081098
  • 语种:English
  • 出版社:MDPI Publishing
  • 摘要:Adherence to the American Cancer Society’s (ACS) Nutrition and Physical Activity Cancer Prevention Guidelines is associated with reductions in overall cancer incidence and mortality, including site-specific cancers such as colorectal cancer. We examined the relationship between baseline adherence to the ACS guidelines and (1) baseline adenoma characteristics and (2) odds of recurrent colorectal adenomas over 3 years of follow-up. Cross-sectional and prospective analyses with a pooled sample of participants from the Wheat Bran Fiber (n = 503) and Ursodeoxycholic Acid (n = 854) trials were performed. A cumulative adherence score was constructed using baseline self-reported data regarding body size, diet, physical activity and alcohol consumption. Multivariable logistic regression demonstrated significantly reduced odds of having three or more adenomas at baseline for moderately adherent (odds ratio [OR] = 0.67, 95% confidence intervals [CI]: 0.46–0.99) and highly adherent (OR = 0.50, 95% CI: 0.31–0.81) participants compared to low adherers (p-trend = 0.005). Conversely, guideline adherence was not associated with development of recurrent colorectal adenoma (moderate adherence OR = 1.16, 95% CI: 0.85–1.59, high adherence OR = 1.23, 95% CI: 0.85–1.79).
  • 关键词:adherence; colorectal adenoma; cancer prevention guidelines; diet; physical activity adherence ; colorectal adenoma ; cancer prevention guidelines ; diet ; physical activity
国家哲学社会科学文献中心版权所有