摘要：The reasons for the increase in both incidence and mortality from malignant melanoma are not clear at this time, although there is an indication of a "generation effect" in the increasing frequency of the disease. The application of an age-period-cohort model to incidence data on malignant melanoma for the State of Connecticut indicate that, unlike mortality, the increase is almost entirely related to period factors. Two explanations are provided to explain this pattern of period factor increase. First, the increase in incidence could be artifically produced by better and earlier diagnosis. Second, a decrease in ozone level in the atmosphere may be responsible for the increase. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (772K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 255 256 257 258 259
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