文章基本信息

标题：Use of Biological Markers and Pharmacokinetics in Human Health Risk Assessment: Biologic markers in risk assessment for environmental carcinogens
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作者：F. Perera ; J. Mayer ; R. M. Santella 等
期刊名称：Environmental Health Perspectives
印刷版ISSN：0091-6765
电子版ISSN：1552-9924
出版年度：1991
卷号：90
页码：247
语种：English
出版社：OCR Subscription Services Inc
摘要：The potential of biologic markers to provide more timely and precise risk assessments for environmental carcinogens is viewed against the current state-of-the-art in biological monitoring/molecular epidemiology. Biologic markers such as carcinogen-DNA adducts and oncogene activation are currently considered valid qualitative indicators of potential risk, but for most chemical exposures research is needed to establish their validity as quantitative predictors of cancer risk. Biologic markers have, however, already provided valuable insights into the magnitude of interindividual variation in response to carcinogenic exposures, with major implications for risk assessment. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.4M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 247 248 249 250 251 252 253 254