文章基本信息

标题：Radiation-induced double-strand modification in calf thymus DNA in the presence of 1,2-dihydroxy-9,10-anthraquinone and its Cu(II) complex.
作者：S Das ; A Saha ; P C Mandal 等
期刊名称：Environmental Health Perspectives
印刷版ISSN：0091-6765
电子版ISSN：1552-9924
出版年度：1997
卷号：105
期号：Suppl 6
页码：1459-1462
语种：English
出版社：OCR Subscription Services Inc
摘要：When cells or DNA is exposed to ionizing radiation, the radicals produced in the irradiated sample will modify the base-pair region of the double strands. Effects of 1,2-dihydroxy-9,10-anthraquinone (DHA) and its Cu(II) complex on the radiation-induced modification of double-strands in calf thymus DNA were studied using ethidium bromide as a fluorescent probe. Our results show that the Cu(II)-DHA complex is more efficient in modifying the base-pair region in double-stranded DNA compared to free DHA. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (816K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 1459 1460 1461 1462