文章基本信息

标题：Alkylated Benzoquinones: Ardisiaquinones A–H from the Leaves of Ardisia quinquegona and Their Anti-Leishmania Activity
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作者：Shintaro Asaumi ; Susumu Kawakami ; Sachiko Sugimoto 等
期刊名称：Chemical and Pharmaceutical Bulletin
印刷版ISSN：0009-2363
电子版ISSN：1347-5223
出版年度：2018
卷号：66
期号：7
页码：757-763
DOI：10.1248/cpb.c18-00281
语种：English
出版社：The Pharmaceutical Society of Japan
摘要：Eight alkylated benzoquinone derivatives, named ardisiaquinones A–H, were isolated together with four known compounds from the leaves of Ardisia quinquegona using a combination of different chromatography techniques. Their structures were elucidated by spectroscopy and by the preparation of methyl ethers. Anti- Leishmania activity and cytotoxicity of the isolated compounds were assayed. Some compounds showed moderate anti- Leishmania activity, however, always associated with cytotoxicity.
关键词：Ardisia quinquegona;Primulaceae;alkylated benzoquinone;anti-Leishmania activity