文章基本信息

标题：An Integrated Receptor Database (IRDB)
本地全文：下载
作者：K Nakata ; T Takai-Igarashi ; T Nakano 等
期刊名称：Data Science Journal
电子版ISSN：1683-1470
出版年度：2015
卷号：1
期号：2
DOI：10.2481/dsj.1.271
语种：English
出版社：Ubiquity Press
摘要：Various receptor data were collected, edited and integrated into an Integrated Receptor Database (IRDB). The data stored includes structural data (amino acid sequences, their secondary-structure and three-dimensional structure), functional data, binding affinity, cell signaling data etc. The purpose of this database is to allow structural biologists, drug designers and toxicologists to analyse and elucidate receptor-ligand dockings and the resultant post-binding signal transduction pathways. IRDB is available on line (http://impact.nihs.go.jp/RDB.html)
关键词：Receptor; Structure; Binding affinity; Cell Signaling; Drug