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标题：Effects of Magnesium and Vitamin B6 on the Severity of Premenstrual Syndrome Symptoms
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作者：Elham Ebrahimi ; Shiva Khayati Motlagh ; Sima Nemati 等
期刊名称：JOURNAL OF CARING SCIENCES
印刷版ISSN：2251-9920
出版年度：2012
卷号：1
期号：4
页码：183-189
DOI：10.5681/jcs.2012.026
语种：English
出版社：TABRIZ UNIVERSITY OF MEDICAL SCIENCES, FACULTY OF NURSING AND MIDWIFERY
摘要：Introduction: The importance of resolving the problem of premenstrual syndrome for patients has been emphasized due to its direct and indirect economical effects on the society. The aim of the current study was to evaluate the effects of magnesium and vitamin B6 on the severity of premenstrual syndrome in patients referring to health centers affiliated to Isfahan University of Medical Sciences, Iran, during 2009-10. Methods: This two-stage double-blind clinical trial was conducted on 126 women who were randomly allocated into 3 groups to receive magnesium, vitamin B6, or placebo. The study was performed in 10 selected health centers in Isfahan and lasted for 4 months. To confirm premenstrual syndrome, the participants were asked to complete a menstrual diary for 2 months at home. Drug interventions were continued for two cycles and the results of before and after the intervention were compared. Results: The findings of this study showed that the mean scores of premenstrual syndrome significantly decreased after the intervention in all groups (p < 0.05). Conclusion: According to our findings, vitamin B6 and placebo had the most and least efficiency in improving the mean premenstrual syndrome score.
关键词：Premenstrual syndrome; Premenstrual tension; Magnesium; Vitamin B6; Placebo