文章基本信息

标题：Novel Bioactive Natural Products Isolated from Madagascar Plants and Marine Organisms (2009–2017)
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作者：Yumin Dai ; Yixi Liu ; L. Harinantenaina Rakotondraibe 等
期刊名称：Chemical and Pharmaceutical Bulletin
印刷版ISSN：0009-2363
电子版ISSN：1347-5223
出版年度：2018
卷号：66
期号：5
页码：469-482
DOI：10.1248/cpb.c17-00395
语种：English
出版社：The Pharmaceutical Society of Japan
摘要：Madagascar’s rain forests and tropical dry forests are home to numerous endemic plant species and the island is considered a biodiversity hotspot. About 80% of the Madagascan (Malagasy) population relies on traditional medicines that have been proven to contain a variety of biologically active compounds. In the search for bioactive compounds from Madagascan biodiversity, we accessed and collected most of the literature dealing with the isolation, structure elucidation, and biological activities of organic small molecules originating from Madagascan plants and marine organisms. Since we published the first review of this work in 2009 ( Curr. Med. Chem. , 17, 2010, Hou and Harinantenaina), the present paper covers the isolation, structures, and bioactivity of 182 new secondary metabolites isolated from Malagasy higher plants and marine organisms in the last seven years (2009–2017).
关键词：bioactive secondary metabolite;natural product;Madagascar