摘要:Human milk is the best food for newborns and infants for its combination of nutrients and biological complexity that allows the healthy grows and development of the infant. These components could be affected by thermic treatments of conservation as heat pasteurization, used in Human Milk Banks. The aim of this study was to evaluate the effects of different treatments applied to human milk in its biological activity (antiradical scavenging and anticancer properties). Human milk was heat pasteurized, also submitted high pressure and after it was spray-dried. Moreover, of UV-C or γ- irradiation was applied on spray dried human milk. HT-29 cell line was used for testing antiproliferative assay. The results of this essay showed that 1.25 mg/mL of human milk treated with high pressures and spray dried can attain CI50. Human milk powder treated with γ-irradiation showed the highest inhibition activity of HT-29 cell line, and the pasteurized and spray dried human milk presents the lowest inhibition activity (p2 anion as compared to all other treatments tested (p 0.05). Spray-dried human milk treated with high pressure, UV-C and γ- irradiation conserved its biological activity, thus it’s could be possible to apply this technology in Human Milk Banks for conserving it.
关键词:human milk; high pressures; UV irradiation; antiproliferative; antioxidant