文章基本信息

标题：Vitamin D and the Liver—Correlation or Cause?
本地全文：下载
作者：Jeremy T. Keane ; Harendran Elangovan ; Rebecca A. Stokes 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2018
卷号：10
期号：4
页码：496
DOI：10.3390/nu10040496
语种：English
出版社：MDPI Publishing
摘要：Vitamin D is becoming increasingly accepted as an important physiological regulator outside of its classical role in skeletal homeostasis. A growing body of evidence connects vitamin D with hepatic disease. This review summarises the role of vitamin D in liver homeostasis and disease and discusses the therapeutic potential of vitamin D-based treatments to protect against hepatic disease progression and to improve response to treatment. While pre-clinical experimental data is promising, clinical trials around liver diseases have mostly been under-powered, and further studies will be required to clarify whether vitamin D or vitamin D analogues have beneficial effects on liver disease.
关键词：vitamin D; VDR; liver fibrosis; NAFLD vitamin D ; VDR ; liver fibrosis ; NAFLD