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标题：HISTOGENESIS OF HUMAN FOETAL PITUITARY AT VARIOUS GESTATIONAL AGES
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作者：S. Babu Rao ; G. Geetha vani ; V. Subhadra Devi. 等
期刊名称：International Journal of Anatomy and Research
印刷版ISSN：2321-4287
出版年度：2017
卷号：5
期号：4
页码：4469-4473
DOI：10.16965/ijar.2017.376
出版社：International Journals of Medical and Health Research
摘要：Introduction: Pituitary gland is the master endocrine gland known for its cellular diversity. The different cells ofpituitary will control different endocrine glands through their secretions. The differential cellular study ofpituitary is important in understanding various diseases that result from hypo or hyper secretion. This studyaims to observe various histological aspects of pituitary at different gestational ages.Materials and Methods: A total of 100 apparently normal dead aborted embryos and fetuses of both sexes of 12to 40 weeks gestational age were utilised for the histological study. The pituitary glands were removed andsubjected to routine Haematoxylin & Eosin procedure. The specimen were categorised and observed forhistogenesis of pituitary at various gestational ages.Results and Conclusion: All the cell types of anterior lobe except lactotrophs are observed at 14 weeks of gestation.Incompletely formed portal vessels are also seen. At 19 weeks, acidophils predominate in lateral region whereasbasophils predominated in middle region. At 24 weeks, the cells of anterior lobe are fully differentiated with theappearance of lactotrophs. Well developed portal vessels are observed. At term, acidophils are comparativelygreater than basophils indicating probably lactotroph hyperplasia due to high maternal oestrogen levels.
关键词：Acidophils; Basophils; Chromophobes; Pituicytes.