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标题：Evaluation of Micronuclei Frequencies and Other Nuclear Alterations in Erythrocytes of Tilapia Rendalli (Perciformes:Cichlidae) Induced By Roundup® Herbicide
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作者：Antonio Adami Pires ; Renata Manelli-Oliveira ; Julio Boschini-Filho 等
期刊名称：Journal of FisheriesSciences.com / Su ÜrünleriBilimeri.com
印刷版ISSN：1307-234X
出版年度：2018
卷号：12
期号：1
页码：29-32
DOI：10.21767/1307-234X.1000144
出版社：Istanbul University
摘要：Micronuclei are chromosome fragments or entire chromosomes that do not incorporate in the main nucleus of thecell, remaining in the cytoplasm after mitosis. Micronucleus tests are usually used to inquire the damage causedin DNA by different external factors. Roundup→ is the most common herbicide used in the world, and it has anactive agent denominated glyphosate that can be responsible for increases of nuclear alterations. The herbicide isa product of Monsanto®, so it does not affect Soya RR, but in natural conditions it could contaminate the aquaticecosystems and its living creatures. The objective of this work was to inquire the frequency of erythrocyteswith micronuclei and other nuclear alterations in the fish Tilapia rendalli induced by the herbicide Roundup®in different concentrations (5 mg/L and 15 mg/L) throughout 5 and 10 days of exposure. The blood cells werecoloured with 15% Giemsa for 15 minutes and the counting was made in an optical microscope. In the presentstudy, the frequency of erythrocytes with micronuclei induced by Roundup® in the treatments are larger thanthose in the control but are not significant (p>0.05). However, when the other nuclei alteration frequencies werecompared with control they demonstrated significant (p<0.05) quantities in the concentrations of 5 and 15 mg/Lalong 5 and 10 days of exposure.
关键词：Micronuclei; Mutagenicity; Roundup; Tilápia; Herbicide