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标题：Paget disease of bone among hospitalized patients in Poland
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作者：Krzysztof Kanecki ; Aneta Nitsch-Osuch ; Paweł Goryński 等
期刊名称：Annals of Agricultural and Environmental Medicine
印刷版ISSN：1232-1966
电子版ISSN：1898-2263
出版年度：2018
卷号：25
期号：1
页码：182-185
DOI：10.26444/aaem/81080
出版社：Institute of Agricultural Medicine in Lublin
摘要：Introduction. Paget’s disease (PDB) is a focal disorder of bone remodeling that occurs commonly in older people withdecreasing prevalence reported in European countries. This disease is most often asymptomatic, but it can cause a varietyof medical complications resulting in considerable morbidity and reduced quality of life. There is little information regardingthe epidemiology of PDB in Poland. To the best of the authors’ knowledge, this is the first large epidemiological analysis ofthis disease in Poland.Objective. The aim of this study was to analyze factors that may be related to the PDB epidemiology among hospitalizedpatients in Poland.Materials and method. The analysis was conducted on the basis of population-based administrative data, taken from aPolish hospital morbidity study carried out by the National Institute of Public Health between January 2008 – December2014.Results. Analyzed data covered 662 hospitalization records. The final study sample comprised 94 (41.8%) male and 131(58.2%) female patients with first-time hospitalizations for PDB, with a significant predominance of females (P<0.02), andthe predominance of patients living in urban (73%) than in rural areas (27%), P<0.001. The average age of the sample was56.8 years (CI: 54.3–59.3; SD 18.8; range 1–93 years). The number of PDB cases hospitalized in Poland significantly decreasedduring the analyzed period of time.Conclusions: PDB is a rare disease with decreasing trends observed among hospitalized patients in Poland. The studyresults may suggest the existence of environmental risk factors for the development of PDB.
关键词：Paget’s disease of bone; hospitalization; rural population; urban population; risk factors.