文章基本信息

标题：Plasma fibroblast growth factor-21 levels in patients with inborn errors of metabolism
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作者：Brian Kirmse ; Juan Cabrerra-Luque ; Omar Ayyub 等
期刊名称：Molecular Genetics and Metabolism Reports
印刷版ISSN：2214-4269
出版年度：2017
卷号：13
页码：52-54
DOI：10.1016/j.ymgmr.2017.04.001
出版社：Elsevier B.V.
摘要：
Fibroblast growth factor-21 (FGF21) levels are elevated in patients with primary mitochondrial disorders but have not been studied in patients with inborn errors of metabolism (IEM) known to have secondary mitochondrial dysfunction. We measured plasma FGF21 by ELISA in patients with and without IEM. FGF21 levels were higher in patients with IEM compared to without IEM (370 pg/dL vs. 0–65 pg/dL). Further study of FGF21 as a biomarker in IEM is warranted.