文章基本信息

标题：Psychological model of ART adherence behaviors in persons living with HIV/AIDS in Mexico: a structural equation analysis
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作者：José Luis Ybarra Sagarduy ; Julio Alfonso Piña López ; Mónica Teresa González Ramírez 等
期刊名称：Revista de Saúde Pública
印刷版ISSN：0034-8910
出版年度：2017
卷号：51
页码：1-12
语种：English
出版社：Universidade de São Paulo
其他摘要：OBJECTIVE: The objective of this study has been to test the ability of variables of a psychological model to predict antiretroviral therapy medication adherence behavior. METHODS: We have conducted a cross-sectional study among 172 persons living with HIV/AIDS (PLWHA), who completed four self-administered assessments: 1) the Psychological Variables and Adherence Behaviors Questionnaire, 2) the Stress-Related Situation Scale to assess the variable of Personality, 3) The Zung Depression Scale, and 4) the Duke-UNC Functional Social Support Questionnaire. Structural equation modeling was used to construct a model to predict medication adherence behaviors. RESULTS: Out of all the participants, 141 (82%) have been considered 100% adherent to antiretroviral therapy. Structural equation modeling has confirmed the direct effect that personality (decision-making and tolerance of frustration) has on motives to behave, or act accordingly, which was in turn directly related to medication adherence behaviors. In addition, these behaviors have had a direct and significant effect on viral load, as well as an indirect effect on CD4 cell count. The final model demonstrates the congruence between theory and data ( x 2 /df. = 1.480, goodness of fit index = 0.97, adjusted goodness of fit index = 0.94, comparative fit index = 0.98, root mean square error of approximation = 0.05), accounting for 55.7% of the variance. CONCLUSIONS: The results of this study support our theoretical model as a conceptual framework for the prediction of medication adherence behaviors in persons living with HIV/AIDS. Implications for designing, implementing, and evaluating intervention programs based on the model are to be discussed.
其他关键词：HIV Long-Term Survivors Acquired; psychology; Medication Adherence; Immunodeficiency Syndrome; drug therapy; Models; Psychological; Patient Medication Knowledge; Health Knowledge; Attitudes; Practice.