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标题：Risk factors for osteoporosis in postmenopausal women – from the point of view of primary care gynecologist
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作者：Damir Franic ; Ivan Verdenik
期刊名称：Slovenian Journal of Public Health
印刷版ISSN：0351-0026
电子版ISSN：1854-2476
出版年度：2018
卷号：57
期号：1
页码：33-38
DOI：10.2478/sjph-2018-0005
语种：English
出版社：Walter de Gruyter GmbH
摘要：Introduction Osteoporosis is a highly prevalent public health problem with osteoporosis-related fractures that account for high morbidity and mortality. Therefore, prevention strategies and early detection of osteoporosis should be carried out in primary gynaecological care units, so as to substantially reduce the risk of fractures and allow the best treatment option for a particular woman. Methods From 2002 to 2011, we recruited 2956 women. Of the total number of women, we additionally extrapolated 1274 women aged 60-75 years, assumingly, the group of women at higher risk of osteoporosis. Demographic and anthropometrical data as well as the information regarding risk factors for osteoporosis were collected using a questionnaire. Results The odds ratio for osteoporosis increased by 8% (p=0.001) with each additional year of life. The OP prevalence increased with age from 24.9% in 60-64 years to 37.4% in 70-75 years. In non-smokers the odds ratio for osteoporosis was 0.424, which was statistically significant (p<0.05). BMI <18.5 increased the odds ratio for osteoporosis by 2 times, which was not statistically significant. In women 60-75 years old (N=1274), the risk of fractures increased with increasing age, considering previous fractures in the last 5 years (p<0.001), hip fracture (p=0.001), wrist fracture (p=0.002) and observed height loss (p<0.001). Hormone therapy (HT) use decreased the prevalence of OP by 25% in comparison with non-users. Conclusion Primary care gynaecologist with a DXA centre has every opportunity for a holistic approach to the management of postmenopausal women, including the prevention and treatment of postmenopausal osteoporosis.
关键词：osteoporosis ; risk factors ; DXA measurements ; the prevention of fractures ; osteoporoza ; dejavniki tveganja ; DXA meritve ; preprečevanje zlomov