文章基本信息

标题：The Neuroprotective Effects of Phenolic Acids: Molecular Mechanism of Action
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作者：Dominik Szwajgier ; Kamila Borowiec ; Katarzyna Pustelniak 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2017
卷号：9
期号：5
页码：477
DOI：10.3390/nu9050477
语种：English
出版社：MDPI Publishing
摘要：The neuroprotective role of phenolic acids from food has previously been reported by many authors. In this review, the role of phenolic acids in ameliorating depression, ischemia/reperfusion injury, neuroinflammation, apoptosis, glutamate-induced toxicity, epilepsy, imbalance after traumatic brain injury, hyperinsulinemia-induced memory impairment, hearing and vision disturbances, Parkinson’s disease, Huntington’s disease, anti-amyotrophic lateral sclerosis, Chagas disease and other less distributed diseases is discussed. This review covers the in vitro, ex vivo and in vivo studies concerning the prevention and treatment of neurological disorders (on the biochemical and gene expression levels) by phenolic acids.
关键词：cinnamic acids; benzoic acids; polyphenols; neuroprotection; neuroinflammation; central nervous system; neuron; glial cell; neurological disorder cinnamic acids ; benzoic acids ; polyphenols ; neuroprotection ; neuroinflammation ; central nervous system ; neuron ; glial cell ; neurological disorder