文章基本信息

标题：EFFECT OF ORAL CONTRACEPTIVES (LD AND CILEST) ON CLOTTING FACTORS VIII AND IX
其他标题：EFFECT OF ORAL CONTRACEPTIVES (LD AND CILEST) ON CLOTTING FACTORS VIII AND IX
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作者：H.R. Sadeghipour Roudsari ; M. Faghihi
期刊名称：Iranian Journal of Public Health
印刷版ISSN：2251-6085
电子版ISSN：2251-6093
出版年度：1997
卷号：26
期号：3-4
页码：25-34
语种：English
出版社：Tehran University of Medical Sciences
摘要：Based on epidemiologic data, women who take oral contraceptives seem to have an increased risk of developing thromboembollic disease. The thrombotic effects of oral contraceptive (OC) are probably mediated, at least partly through their effects on the coagulation system. Plasma levels of several clotting factors have been shown to be elevated in OC users, and this increase is graduated according to the dose of estrogen. In this study, fifty healthy and non smoking women, aged 18-35 years, were randomly assigned to treatment with 2 different OCs: a monophasic pill containing 30 pg of ethinyl estradiol plus 150µg levonorgestrel (LD) and a monophasic pill containing 35µg ethinylestradiol plus 250pg norgestimate (Cilest). Factor VIII plasma values were significantly decreased (P
关键词：Oral contraceptive