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标题：Major depressive disorder and associated factors in elderly patients with non-Hodgkin’s lymphoma
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作者：Carolina Baeza-Velasco ; Fanny Baguet ; Priscilla Allart 等
期刊名称：Health Psychology and Behavioral Medicine: An Open Access Journal
电子版ISSN：2164-2850
出版年度：2017
卷号：5
期号：1
页码：57-65
DOI：10.1080/21642850.2016.1264879
语种：English
出版社：Taylor and Francis Ltd
摘要：ABSTRACT Background: Data regarding elderly patients with cancer, more particularly with non-Hodgkin’s lymphomas (NHL), are scarce, as is our knowledge concerning to comorbid depression in this population. The purpose of this work was to explore the frequency of major depressive disorder (MDD) and related factors in a group of elderly patients with these forms of cancer. Method : 42 elderly NHL patients aged 70 years and older were interviewed using the Mini International Neuropsychiatric Interview screening tool. Psychological variables such as coping strategies, cognitive status and quality of relationships, as well as clinical and socio-demographic data were collected. Results: Fourteen patients (33.3%) met criteria for current MDD of which five had melancholy features (35.7%). Elderly patients with comorbid NHL-MDD had a significantly poorer self-perceived global health and performance status than those without MDD, as well as more fatigue and history of depression. No other clinical, psychological or socio-demographic variable appeared associated with MDD in this sample. Conclusion: Further studies are needed in order to confirm these early results concerning a potential high frequency of MDD among elderly NHL patients. Depressive mood should be early recognized in order to provide appropriate treatments and avoid a detrimental effect of depression on cancer prognosis.
关键词：Depression ; cancer ; non-Hodgkin's lymphoma ; elderly