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标题：Multicomponent Reactions: Microwave-assisted Efficient Synthesis of Dihydropyrimidinones (thiones) and Quinazolinones under Green Chemistry Protocol as Probes for Antimicrobial Activities
其他标题：Multicomponent Reactions: Microwave-assisted Efficient Synthesis of Dihydropyrimidinones (thiones) and Quinazolinones under Green Chemistry Protocol as Probes for Antimicrobial Activities
作者：M. H. Bhuiyan ; H. Nessa ; M. M. Mahmud 等
期刊名称：Journal of Scientific Research
印刷版ISSN：2070-0237
电子版ISSN：2070-0245
出版年度：2012
卷号：4
期号：1
页码：143
DOI：10.3329/jsr.v4i1.8688
语种：English
出版社：Rajshahi University
摘要：Microwave promoted diammonium hydrogen phosphate, (NH4)2HPO4, catalyzed three-component Biginelli reaction between an aldehyde, a 1,3-dicarbonyl compound and urea or thiourea under solvent-free conditions afforded the corresponding dihydropyrimidinones and quinazolinones in high yields. The synthesized compounds have been screened for their antimicrobial activity against Pseudomonas aeruginosa, Staphylococcus aureus, Vibrio choloriae, Shigella dysenteriae, Salmonella typhi bacteria and Aspargilllus flavus, Saccharomyces cerevisiae and Candida albicans fungi respectively. Some of the synthesized compounds exhibited pronounced antimicrobial activities.Keywords: Multicomponent reactions; Dihydropyrimidinone; Microwave irradiation; Antimicrobial activity.© 2012 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.doi: http://dx.doi.org/10.3329/jsr.v4i1.8688J. Sci. Res. 4 (1), 143-153 (2012)
关键词：Chemistry;Multicomponent reactions; Dihydropyrimidinone; Microwave irradiation; Antimicrobial activity.