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文章基本信息

  • 标题:Creating transplant tolerance by taming adverse intragraft innate immunity
  • 作者:Dusan Hanidziar ; Maria Koulmanda ; Terry B Strom
  • 期刊名称:F1000 Biology Reports
  • 电子版ISSN:2051-7599
  • 出版年度:2010
  • 卷号:2
  • DOI:10.3410/B2-83
  • 出版社:Faculty of 1000 Ltd
  • 摘要:Certain forms of inflammation of an allograft are highly detrimental to the induction and maintenance of transplant tolerance as they foster stable commitment to graft-destructive, not graft-protective, forms of T-cell immunity. Hence, a reduction in adverse tissue inflammation may prove crucial in facilitating the induction and maintenance of a long-lasting state of transplant tolerance.
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