文章基本信息

标题：Validation of a Method for Simultaneous Determination of Acetaminophen and Caffeine by HPLC in Different Pharmaceutical Forms: Tablet, Capsule and Sachet
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作者：Radi M. ; Ramli Y. ; El Karbane M. 等
期刊名称：Journal of Materials and Environmental Science
印刷版ISSN：2028-2508
出版年度：2016
卷号：7
期号：12
页码：4608-4613
出版社：University of Mohammed Premier Oujda
摘要：A simple, fast, economical, accurate, precise and reproducible RP – HPLC method was developed for thesimultaneous estimation of acetaminophen (AAPH) and caffeine (CAF) in starting materialand pharmaceuticaldosage forms. The method was validated in terms of specificity, linearity, precision accuracy, and robustness. Theproposed method’s results were found to be satisfactory and are suitable for determination of acetaminophen andcaffeine for routine quality control of drugs in formulations.
关键词：acetaminophen; caffeine; HPLC; validation