文章基本信息

标题：Osmotic pressure contribution of albumin to colloidal interactions
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作者：Mukta Singh-Zocchi ; Anita Andreasen ; Giovanni Zocchi 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1999
卷号：96
期号：12
页码：6711-6715
DOI：10.1073/pnas.96.12.6711
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Two surfaces that come in close contact in a solution with macromolecules present experience an attractive force caused by the osmotic pressure. We present a measurement of this effect by using a micrometer-sized sphere bound to a flat plate through a single molecular attachment in an albumin-containing solution. We obtain the osmotic part of the interaction potential with a resolution of <1 nm and a fraction of kTroom. This attractive interaction is seen to have a range comparable to the size of the albumin molecule. The results are broadly in agreement with a geometric model first proposed by Asakura and Oosawa.