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  • 标题:Activation of protein kinase C by tyrosine phosphorylation in response to H2O2
  • 本地全文:下载
  • 作者:Hiroaki Konishi ; Motonari Tanaka ; Yukitoshi Takemura
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1997
  • 卷号:94
  • 期号:21
  • 页码:11233-11237
  • DOI:10.1073/pnas.94.21.11233
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Protein kinase C (PKC) isoforms, , {beta}I, and {gamma} of cPKC subgroup, {delta} and {varepsilon} of nPKC subgroup, and {zeta} of aPKC subgroup, were tyrosine phosphorylated in COS-7 cells in response to H2O2. These isoforms isolated from the H2O2-treated cells showed enhanced enzyme activity to various extents. The enzymes, PKC and {delta
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