期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:1997
卷号:94
期号:21
页码:11233-11237
DOI:10.1073/pnas.94.21.11233
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:Protein kinase C (PKC) isoforms, , {beta}I, and {gamma} of cPKC subgroup, {delta} and {varepsilon} of nPKC subgroup, and {zeta} of aPKC subgroup, were tyrosine phosphorylated in COS-7 cells in response to H2O2. These isoforms isolated from the H2O2-treated cells showed enhanced enzyme activity to various extents. The enzymes, PKC and {delta