文章基本信息

标题：Human nucleolus organizers on nonhomologous chromosomes can share the same ribosomal gene variants
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作者：M Krystal ; P D'Eustachio ; F H Ruddle 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1981
卷号：78
期号：9
页码：5744-5748
DOI：10.1073/pnas.78.9.5744
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：The distributions of three human ribosomal gene polymorphisms among individual chromosomes containing nucleolus organizers were analyzed by using mouse--human hybrid cells. Different nucleolus organizers can contain the same variant, suggesting the occurrence of genetic exchanges among ribosomal gene clusters on nonhomologous chromosomes. Such exchanges appear to occur less frequently in mice. This difference is discussed in terms of the nucleolar organization and chromosomal location of ribosomal gene clusters in humans and mice.