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标题：Immunohistochemical localization of renin in luteinizing hormone-producing cells of rat pituitary
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作者：K Naruse ; Y Takii ; T Inagami 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1981
卷号：78
期号：12
页码：7579-7583
DOI：10.1073/pnas.78.12.7579
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：The location of renin (EC 3.4.99.19 ) in rat pituitary was determined by the peroxidase-antiperoxidase immunohistochemical technique. By using antisera prepared with purified rat renal renin, an immunoreactive substance was localized within ovoid cells scattered throughout the anterior pituitary. These cells were shown to be luteinizing hormone-producing cells by staining with anti-luteinizing hormone antisera in adjacent sections. By using the double staining method, the renin-containing cells were differentiated from cells containing corticotropin, thyrotropin, growth hormone (somatotropin), and prolactin (mammotropin). These results suggest a possible local role for renin in the anterior pituitary.