文章基本信息

标题：Search for mutations affecting protein structure in children of atomic bomb survivors: preliminary report
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作者：J V Neel ; C Satoh ; H B Hamilton 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1980
卷号：77
期号：7
页码：4221-4225
DOI：10.1073/pnas.77.7.4221
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：A total of 289,868 locus tests, based on 28 different protein phenotypes and using one-dimensional electrophoresis to detect variant proteins, has yielded one probable mutation in the offspring of "proximally exposed" parents, who received an estimated average gonadal exposure of 31 to 39 rem in the atomic bombings of Hiroshima and Nagasaki. There were no mutations in 208,196 locus tests involving children of "distally exposed" parents, who had essentially no radiation exposure.