文章基本信息

标题：Measurement of changes in high-energy phosphates in the cardiac cycle using gated 31P nuclear magnetic renonance
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作者：E T Fossel ; H E Morgan ; J S Ingwall 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1980
卷号：77
期号：6
页码：3654-3658
DOI：10.1073/pnas.77.6.3654
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Levels of the high-energy phosphate-containing compounds, ATP and creatine phosphate, and of inorganic phosphate (Pi) were measured as a function of position in the cardiac cycle. Measurements were made on isolated, perfused, working rat hearts through the use of gated 31P nuclear magnetic resonance spectroscopy. Levels of ATP and creatine phosphate were found to vary during the cardiac cycle and were maximal at minimal aortic pressure and minimal at maximal aortic pressure. Pi varied inversely with the high-energy phosphates.